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Nonoxidative Phase of the Pentose Phosphate Pathway The nonoxidative reactions of this pathway are reversible reactions that allow intermediates of glycolysis (specifically, glyceraldehyde 3-P and fructose 6-P) to be converted to five-carbon sugars (such as ribose 5-P), and vice versa

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569,570 In contrast, podocyte-specific VEGF-C overexpression in diabetic mice improves albuminuria and endothelial function by lowering VEGFR2, 571,572 while elevated VEGF-D correlates with renal impairment, albuminuria, and proteinuria